Mediterranean diet cost
The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events. Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. On the basis of the results of an interim analysis, the trial was stopped after a median follow-up of 4. A primary end-point event occurred in 288 participants. All participants provided written informed consent. org. Full Text of Methods. Details of the trial design are provided elsewhere. 10-12 The trial was designed and conducted by the authors, and the protocol was approved by the institutional review boards at all study locations. The two Mediterranean-diet groups had good adherence to the intervention, according to self-reported intake and biomarker analyses. All participants provided written informed consent.
Beginning on October 1, 2003, participants were randomly assigned, in a 1:1:1 ratio, to one of three dietary intervention groups: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with nuts, or a control diet. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). None of the sponsors had any role in the trial design, data analysis, or reporting of the results. Full Text of Methods. A primary end-point event occurred in 288 participants. org. The primary end point was the rate of major cardiovascular events (myocardial infarction, stroke, or death from cardiovascular causes). Participants received quarterly individual and group educational sessions and, depending on group assignment, free provision of extra-virgin olive oil, mixed nuts, or small nonfood gifts. 8 years. Methods In a multicenter trial in Spain, we randomly assigned participants who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet (advice to reduce dietary fat). Beginning on October 1, 2003, participants were randomly assigned, in a 1:1:1 ratio, to one of three dietary intervention groups: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with nuts, or a control diet. Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. None of the sponsors had any role in the trial design, data analysis, or reporting of the results. Detailed enrollment criteria are provided in the Supplementary Appendix, available at NEJM. Abstract Background Observational cohort studies and a secondary prevention trial have shown an inverse association between adherence to the Mediterranean diet and cardiovascular risk. 8 years. Details of the trial design are provided elsewhere.
